Manfred Westphal Selected Research

Hypoxia (Hypoxemia)

11/2013	Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells.
7/2007	Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration.

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Manfred Westphal Research Topics

Disease

83	Neoplasms (Cancer) 05/2024 - 01/2002
64	Glioblastoma (Glioblastoma Multiforme) 05/2024 - 01/2002
49	Glioma (Gliomas) 05/2024 - 01/2002
16	Brain Neoplasms (Brain Tumor) 01/2024 - 10/2003
7	Astrocytoma (Pilocytic Astrocytoma) 01/2024 - 04/2003
7	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2023 - 08/2014
7	Neoplasm Metastasis (Metastasis) 10/2022 - 07/2014
6	Parkinson Disease (Parkinson's Disease) 01/2023 - 01/2013
6	Meningioma (Meningiomas) 12/2022 - 03/2016
5	Hydrocephalus (Hydrocephaly) 01/2023 - 01/2018
4	Aneurysm (Aneurysms) 09/2023 - 01/2019
4	Traumatic Brain Injuries (Traumatic Brain Injury) 05/2023 - 04/2016
4	Circulating Neoplastic Cells 11/2022 - 07/2014
4	Ependymoma 08/2021 - 04/2005
4	Hemorrhage 01/2018 - 01/2014
3	Wounds and Injuries (Trauma) 05/2023 - 11/2015
3	Seizures (Absence Seizure) 11/2022 - 01/2008
3	Pain (Aches) 05/2022 - 12/2009
3	Edema (Dropsy) 10/2021 - 12/2009
3	Infections 01/2021 - 01/2018
3	Necrosis 11/2018 - 08/2003
3	Residual Neoplasm 04/2017 - 02/2004
3	Disease Progression 01/2017 - 02/2004
2	COVID-19 01/2024 - 12/2021
2	Chronic Subdural Hematoma 12/2023 - 03/2018
2	Brain Ischemia (Cerebral Ischemia) 01/2023 - 10/2022
2	Inflammation (Inflammations) 12/2022 - 12/2017
2	Headache Disorders (Headache Syndromes) 05/2022 - 12/2015
2	Epilepsy (Aura) 12/2021 - 06/2019
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2020 - 04/2016
2	Carcinoma (Carcinomatosis) 12/2017 - 01/2017

Drug/Important Bio-Agent (IBA)

19	Biomarkers (Surrogate Marker)IBA 04/2024 - 12/2007
17	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 06/2010
13	Proteins (Proteins, Gene)FDA Link 12/2022 - 12/2003
10	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2024 - 12/2009
10	ErbB Receptors (EGF Receptor)IBA 11/2017 - 07/2005
9	LigandsIBA 01/2017 - 10/2003
8	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 06/2011
7	epidermal growth factor receptor VIIIIBA 10/2023 - 09/2008
6	EnzymesIBA 03/2020 - 02/2002
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2024 - 04/2003
5	Epidermal Growth Factor (EGF)IBA 09/2017 - 06/2003
5	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2017 - 06/2003
5	Carmustine (FIVB)FDA Link 06/2011 - 01/2003
4	Indicators and Reagents (Reagents)IBA 04/2024 - 11/2004
4	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2022 - 10/2003
4	MethyltransferasesIBA 01/2021 - 08/2011
4	Alkylating AgentsIBA 03/2020 - 09/2012
4	AntigensIBA 01/2018 - 04/2005
4	poliferprosan 20 drug combination carmustine (Gliadel)FDA Link 01/2011 - 01/2003
4	Complementary DNA (cDNA)IBA 01/2008 - 10/2003
4	pleiotrophin (HARP)IBA 09/2006 - 06/2003
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2005 - 06/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2024 - 08/2016
3	CytokinesIBA 01/2024 - 11/2018
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2024 - 01/2018
3	Oxygen (Dioxygen)IBA 10/2022 - 04/2012
3	Bevacizumab (Avastin)FDA Link 03/2020 - 01/2017
3	Epithelial Cell Adhesion MoleculeIBA 01/2019 - 01/2017
3	nimotuzumabIBA 01/2018 - 12/2012
3	Tyrosine Kinase InhibitorsIBA 09/2017 - 10/2013
3	Monoclonal AntibodiesIBA 09/2017 - 07/2005
3	Protein Tyrosine PhosphatasesIBA 09/2006 - 12/2003
3	Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA 09/2006 - 12/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2023 - 09/2019
2	Analgesics (Analgesic Drugs)IBA 05/2022 - 12/2009
2	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2022 - 11/2015
2	SteroidsIBA 10/2021 - 08/2018
2	TitaniumIBA 08/2021 - 01/2021
2	Nimodipine (Modus)FDA LinkGeneric 01/2021 - 05/2015
2	O-(6)-methylguanineIBA 01/2021 - 04/2017
2	ProdrugsIBA 10/2019 - 08/2013
2	Ganciclovir (Cytovene)FDA LinkGeneric 10/2019 - 08/2013
2	Thymidine KinaseIBA 10/2019 - 08/2013
2	Small Interfering RNA (siRNA)IBA 04/2019 - 09/2006
2	Peptides (Polypeptides)IBA 01/2018 - 05/2015
2	VaccinesIBA 01/2018 - 01/2018
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2017 - 02/2016
2	MicroRNAs (MicroRNA)IBA 12/2016 - 10/2015
2	AntibodiesIBA 02/2016 - 07/2014
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2016 - 10/2013
2	Insulin-Like PeptidesIBA 08/2015 - 06/2003

Therapy/Procedure

39	Therapeutics 01/2024 - 01/2002
20	Drug Therapy (Chemotherapy) 04/2024 - 01/2003
12	Radiotherapy 01/2023 - 01/2005
10	Deep Brain Stimulation 01/2023 - 01/2009
7	Immunotherapy 10/2021 - 04/2010
6	Chemoradiotherapy 08/2021 - 01/2009
5	Craniotomy 03/2023 - 01/2016
4	Decompressive Craniectomy 08/2021 - 04/2016
3	Diskectomy (Discectomy) 06/2012 - 12/2006
3	Catheters 01/2011 - 08/2010
2	Heterologous Transplantation (Xenotransplantation) 05/2024 - 08/2023
2	Neurosurgical Procedures 12/2023 - 01/2023
2	Blood Transfusion (Blood Transfusions) 09/2023 - 01/2021
2	Extracorporeal Membrane Oxygenation 05/2023 - 12/2021
2	Critical Care (Surgical Intensive Care) 05/2023 - 01/2014
2	Ventriculoperitoneal Shunt 01/2023 - 01/2023
2	Decompression 09/2020 - 12/2009
2	Laminectomy 08/2017 - 12/2009